Postmarketing circumstances of respiratory despair, which include fatalities, happen to be noted with use of promethazine hydrochloride in pediatric patients below 2 decades of age. A wide array of body weight-based doses of promethazine hydrochloride have resulted in respiratory despair in these clients.
Warning ought to be exercised when promethazine hydrochloride and codeine phosphate syrup is administered to your nursing woman.
It is tricky to ascertain what constitutes a normal poisonous or lethal dose. Having said that, the lethal oral dose of codeine in an Grownup is noted to generally be during the range of 0.
Due to the prospective for fatal respiratory depression, don't administer promethazine and codeine concurrently to little ones Tier
This medication can dry up and thicken mucus in your lungs, making it harder to breathe and very clear your lungs. To help you reduce this outcome, consume a lot of fluids Except in any other case directed by your doctor.
Codeine has superior antitussive exercise, although under that of morphine at equivalent doses. It is Employed in choice to morphine, because Uncomfortable side effects are infrequent at the same old antitussive dose of codeine.
Promethazine administered to a Expecting lady inside two months of supply could inhibit platelet aggregation in the newborn.
Decrease Seizure Threshold – Promethazine may well lessen seizure threshold. It should be utilised with warning in folks with seizure Issues or in individuals who are employing concomitant remedies, for example narcotics or local anesthetics, which may also impact seizure threshold.
Allergy symptoms Explain to your health practitioner When you have ever had any uncommon or allergic reaction to this drugs or any other medicines.
A healthcare professional really should be consulted just before having any Promethazine codeine syrup drug, changing any eating plan or commencing or discontinuing any study course of remedy.
A special MedGuide will probably be presented to you because of the pharmacist with Each and every prescription and refill. Make sure to read this data diligently each time.
The combination of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric patients fewer than 6 decades of age, because the combination may perhaps lead to deadly respiratory depression In this particular age inhabitants (see WARNINGS Box Warning and Use in Pediatric People).
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This medication could interfere with specified lab checks (which include some pregnancy exams, blood sugar exams, amylase/lipase amounts), possibly creating Wrong check effects. Make certain lab staff and your Medical professionals know you use this drug.